Molecular Formula | C96H122N18O16 |
Molar Mass | 1784.11 |
Storage Condition | -20°C,干燥,密封 |
biological activity | 187-1, N-WASP, it is also an inhibitor of the allosteric neural Wiskott Aldrich syndrome protein (N-WASP). N-WASP -1, inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4, 5-bisphosphate (PIP2) with an IC50 of 2 μm. N-WASP -1, N-WASP inhibitor prevented from activating Arp2/3 by stabilizing the self-inhibitory state of the protein. |